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Biosynthesis of HLA-C heavy chains in melanoma cells with multiple defects in the expression of HLA-A, -B, -C molecules
Recent investigations have shown that malignant transformation may down-regulate the expression of class I HLA molecules, β(2)-microglobulin (β(2)m) and members of the antigen-processing machinery. In the present study, we HLA-genotyped and identified at a biochemical level the three (HLA-A25, -B8,...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1999
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362293/ https://www.ncbi.nlm.nih.gov/pubmed/10360639 http://dx.doi.org/10.1038/sj.bjc.6690405 |