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The sulfhydryl containing compounds WR-2721 and glutathione as radio- and chemoprotective agents. A review, indications for use and prospects

Radio- and chemotherapy for the treatment of malignancies are often associated with significant toxicity. One approach to reduce the toxicity is the concomitant treatment with chemoprotective agents. This article reviews two sulfhydryl compounds, namely the agent WR-2721 (amifostine), a compound rec...

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Detalles Bibliográficos
Autores principales: Hospers, G A P, Eisenhauer, E A, Vries, E G E de
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362304/
https://www.ncbi.nlm.nih.gov/pubmed/10360638
http://dx.doi.org/10.1038/sj.bjc.6690404