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Cytochrome P450 1A1 genetic polymorphisms and risk of hepatocellular carcinoma among chronic hepatitis B carriers

Cigarette smoking has been associated with increased risk of hepatocellular carcinoma (HCC) in some epidemiological studies. Cytochrome P450 1A1 (CYP1A1) is involved in the biotransformation of tobacco-derived polycyclic aromatic hydrocarbons (PAHs) into carcinogenic metabolites. The aim of this stu...

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Detalles Bibliográficos
Autores principales: Yu, M-W, Chiu, Y-H, Yang, S-Y, Santella, R M, Chern, H-D, Liaw, Y-F, Chen, C-J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362308/
https://www.ncbi.nlm.nih.gov/pubmed/10408872
http://dx.doi.org/10.1038/sj.bjc.6690397