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Mutation and deletion analysis of GFRα-1, encoding the co-receptor for the GDNF/RET complex, in human brain tumours

Glial cell line-derived neurotrophic factor (GDNF) plays a key role in the control of vertebrate neuron survival and differentiation in both the central and peripheral nervous systems. GDNF preferentially binds to GFRα-1 which then interacts with the receptor tyrosine kinase RET. We investigated a p...

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Detalles Bibliográficos
Autores principales: Gimm, O, Gössling, A, Marsh, D J, Dahia, P L M, Mulligan, L M, Deimling, A von, Eng, C
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362327/
https://www.ncbi.nlm.nih.gov/pubmed/10408842
http://dx.doi.org/10.1038/sj.bjc.6690367