Mismatch repair deficiency is associated with resistance to DNA minor groove alkylating agents

Mismatch DNA repair deficiency is associated with resistance to certain major groove alkylating agents including methylating agents and cisplatin. We have now studied the relevance of mismatch repair alterations to the cytotoxicity induced by drugs which alkylate N3 adenines in the minor groove of D...

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Detalles Bibliográficos
Autores principales: Colella, G, Marchini, S, D'Incalci, M, Brown, R, Broggini, M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362350/
https://www.ncbi.nlm.nih.gov/pubmed/10408835
http://dx.doi.org/10.1038/sj.bjc.6690360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362350/
https://www.ncbi.nlm.nih.gov/pubmed/10408835
http://dx.doi.org/10.1038/sj.bjc.6690360

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