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Mismatch repair deficiency is associated with resistance to DNA minor groove alkylating agents
Mismatch DNA repair deficiency is associated with resistance to certain major groove alkylating agents including methylating agents and cisplatin. We have now studied the relevance of mismatch repair alterations to the cytotoxicity induced by drugs which alkylate N3 adenines in the minor groove of D...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
1999
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362350/ https://www.ncbi.nlm.nih.gov/pubmed/10408835 http://dx.doi.org/10.1038/sj.bjc.6690360 |