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Anti-tumour activity in vitro and in vivo of selective differentiating agents containing hydroxamate
A series of hydroxamates, which are not metalloprotease inhibitors, have been found to be selectively toxic to a range of transformed and human tumour cells without killing normal cells (fibroblasts, melanocytes) at the same concentrations. Within 24 h of treatment, drug action is characterized by m...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1999
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362353/ https://www.ncbi.nlm.nih.gov/pubmed/10376979 http://dx.doi.org/10.1038/sj.bjc.6690493 |