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Cyclin D1 expression in non-small-cell lung cancers: its association with altered p53 expression, cell proliferation and clinical outcome

Cyclin D1, like p16(INK4) (p16) and retinoblastoma (RB) proteins, participates in the cell cycle control at the G1–S transition. We have previously demonstrated altered p16 and RB protein status in non-small-cell lung cancers (NSCLCs) and their potential synergistic effect with altered p53 protein o...

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Detalles Bibliográficos
Autores principales: Mishina, T, Dosaka-Akita, H, Kinoshita, I, Hommura, F, Morikawa, T, Katoh, H, Kawakami, Y
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362358/
https://www.ncbi.nlm.nih.gov/pubmed/10376986
http://dx.doi.org/10.1038/sj.bjc.6990500