Rapid induction of p21(WAF1) but delayed down-regulation of Cdc25A in the TGF-β-induced cell cycle arrest of gastric carcinoma cells

Transforming growth factor-β (TGF-β) is a multifunctional polypeptide that inhibits cellular proliferation in most epithelial cells. cdk4 and several cyclin-dependent kinase (cdk) inhibitors (p15(INK4B), p21(WAF1/Cip1) and p27(Kip1)) have been implicated in the TGF-β-induced cell cycle arrest. More...

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Detalles Bibliográficos
Autores principales: Kang, S H, Bang, Y-J, Jong, H-S, Seo, J Y, Kim, N K, Kim, S-J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362369/
https://www.ncbi.nlm.nih.gov/pubmed/10376964
http://dx.doi.org/10.1038/sj.bjc.6690478

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362369/
https://www.ncbi.nlm.nih.gov/pubmed/10376964
http://dx.doi.org/10.1038/sj.bjc.6690478

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