A photodynamic pathway to apoptosis and necrosis induced by dimethyl tetrahydroxyhelianthrone and hypericin in leukaemic cells: possible relevance to photodynamic therapy

The mechanism of cell death induction by dimethyl tetrahydroxyhelianthrone (DTHe), a new second-generation photodynamic sensitizer, is analysed in human leukaemic cell lines in comparison with the structurally related hypericin. DTHe has a broad range of light spectrum absorption that enables effect...

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Detalles Bibliográficos
Autores principales: Lavie, G, Kaplinsky, C, Toren, A, Aizman, I, Meruelo, D, Mazur, Y, Mandel, M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362416/
https://www.ncbi.nlm.nih.gov/pubmed/10027308
http://dx.doi.org/10.1038/sj.bjc.6690066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362416/
https://www.ncbi.nlm.nih.gov/pubmed/10027308
http://dx.doi.org/10.1038/sj.bjc.6690066

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