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Genomic structure and alterations of homeobox gene CDX2 in colorectal carcinomas

Expression of CDX2, a caudal-related homeobox gene, was found to be decreased in colorectal carcinomas. Heterozygous null mutant mice as to Cdx2 develop multiple intestinal adenomatous polyps. To clarify the role of CDX2 in colorectal carcinogenesis, we determined its genomic structure, and searched...

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Detalles Bibliográficos
Autores principales: Yagi, O K, Akiyama, Y, Yuasa, Y
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362430/
https://www.ncbi.nlm.nih.gov/pubmed/10027310
http://dx.doi.org/10.1038/sj.bjc.6690068