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Genomic structure and alterations of homeobox gene CDX2 in colorectal carcinomas
Expression of CDX2, a caudal-related homeobox gene, was found to be decreased in colorectal carcinomas. Heterozygous null mutant mice as to Cdx2 develop multiple intestinal adenomatous polyps. To clarify the role of CDX2 in colorectal carcinogenesis, we determined its genomic structure, and searched...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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Nature Publishing Group
1999
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362430/ https://www.ncbi.nlm.nih.gov/pubmed/10027310 http://dx.doi.org/10.1038/sj.bjc.6690068 |