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p53 mutations in human cutaneous melanoma correlate with sun exposure but are not always involved in melanomagenesis

In melanoma, the relationship between sun exposure and the origin of mutations in either the N-ras oncogene or the p53 tumour-suppressor gene is not as clear as in other types of skin cancer. We have previously shown that mutations in the N-ras gene occur more frequently in melanomas originating fro...

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Detalles Bibliográficos
Autores principales: Zerp, S F, Elsas, A van, Peltenburg, L T C, Schrier, P I
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362648/
https://www.ncbi.nlm.nih.gov/pubmed/10070891
http://dx.doi.org/10.1038/sj.bjc.6690147