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Mutation in the PTEN/MMAC1 gene in archival low grade and high grade gliomas

The PTEN gene, located on 10q23.3, has recently been described as a candidate tumour suppressor gene that may be important in the development of advanced cancers, including gliomas. We have investigated mutation in the PTEN gene by direct sequence analysis of PCR products amplified from samples micr...

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Detalles Bibliográficos
Autores principales: Davies, M P A, Gibbs, F E M, Halliwell, N, Joyce, K A, Roebuck, M M, Rossi, M L, Salisbury, J, Sibson, D R, Tacconi, L, Walker, C
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362705/
https://www.ncbi.nlm.nih.gov/pubmed/10188904
http://dx.doi.org/10.1038/sj.bjc.6690246