The flavonoid galangin is an inhibitor of CYP1A1 activity and an agonist/antagonist of the aryl hydrocarbon receptor

The effect of the dietary flavonoid galangin on the metabolism of 7,12-dimethylbenz[a]anthracene (DMBA), the activity of cytochrome P (450) 1A1 (CYP1A1), and the expression of CYP1A1 in MCF-7 human breast carcinoma cells was investigated. Galangin inhibited the catabolic breakdown of DMBA, as measur...

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Detalles Bibliográficos
Autores principales: Ciolino, H P, Yeh, G C
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362711/
https://www.ncbi.nlm.nih.gov/pubmed/10188874
http://dx.doi.org/10.1038/sj.bjc.6690216

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362711/
https://www.ncbi.nlm.nih.gov/pubmed/10188874
http://dx.doi.org/10.1038/sj.bjc.6690216

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