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Increased transcriptional activity of prostate-specific antigen in the presence of TNP-470, an angiogenesis inhibitor
Prostate-specific antigen, PSA, is regarded as a reliable surrogate marker for androgen-independent prostate cancer (AIPC). Concern has been raised that investigational agents may affect PSA secretion without altering tumour growth or volume. In a phase I trial, several patients with AIPC had elevat...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1999
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362736/ https://www.ncbi.nlm.nih.gov/pubmed/10188911 http://dx.doi.org/10.1038/sj.bjc.6690253 |