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Increased transcriptional activity of prostate-specific antigen in the presence of TNP-470, an angiogenesis inhibitor

Prostate-specific antigen, PSA, is regarded as a reliable surrogate marker for androgen-independent prostate cancer (AIPC). Concern has been raised that investigational agents may affect PSA secretion without altering tumour growth or volume. In a phase I trial, several patients with AIPC had elevat...

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Detalles Bibliográficos
Autores principales: Horti, J, Dixon, S C, Logothetis, C J, Guo, Y, Reed, E, Figg, W D
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362736/
https://www.ncbi.nlm.nih.gov/pubmed/10188911
http://dx.doi.org/10.1038/sj.bjc.6690253