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Specificity analysis of sera from breast cancer patients vaccinated with MUC1-KLH plus QS-21

The mucin MUC1 is expressed on breast cancers in an underglycosylated form compared to normal tissues and is therefore a potential target for cancer immunotherapy. MUC1 contains multiple tandem repeats of the 20 amino acid (aa) peptide (VTSAPDTRPAPGSTAPPAHG). The APDTRPA epitope is particularly immu...

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Detalles Bibliográficos
Autores principales: Adluri, S, Gilewski, T, Zhang, S, Ramnath, V, Ragupathi, G, Livingston, P
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362788/
https://www.ncbi.nlm.nih.gov/pubmed/10206297
http://dx.doi.org/10.1038/sj.bjc.6990288