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Caspase I-related protease inhibition retards the execution of okadaic acid- and camptothecin-induced apoptosis and PAI-2 cleavage, but not commitment to cell death in HL-60 cells

We have previously reported that the putative cytoprotective protease inhibitor, plasminogen activator inhibitor type 2 (PAI-2), is specifically cleaved during okadaic acid-induced apoptosis in a myeloid leukaemic cell line (Br J Cancer (1994) 70: 834–840). HL-60 cells exposed to okadaic acid and ca...

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Detalles Bibliográficos
Autores principales: Jensen, P H, Fladmark, K E, Gjertsen, B T, Vintermyr, O K
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362792/
https://www.ncbi.nlm.nih.gov/pubmed/10206278
http://dx.doi.org/10.1038/sj.bjc.6690269