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The prognostic significance of allelic imbalance at key chromosomal loci in oral cancer

Forty-eight primary oral squamous cell carcinomas (SCC) were screened for allelic imbalance (AI) at 3p24–26, 3p21, 3p13, 8p21–23, 9p21, 9q22 and within the Rb, p53 and DCC tumour suppressor genes. AI was detected at all TNM stages with stage 4 tumours showing significantly more aberrations than stag...

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Detalles Bibliográficos
Autores principales: Partridge, M, Emilion, G, Pateromichelakis, S, A'Hern, R, Lee, G, Phillips, E, Langdon, J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362810/
https://www.ncbi.nlm.nih.gov/pubmed/10206299
http://dx.doi.org/10.1038/sj.bjc.6990290