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The prognostic significance of allelic imbalance at key chromosomal loci in oral cancer
Forty-eight primary oral squamous cell carcinomas (SCC) were screened for allelic imbalance (AI) at 3p24–26, 3p21, 3p13, 8p21–23, 9p21, 9q22 and within the Rb, p53 and DCC tumour suppressor genes. AI was detected at all TNM stages with stage 4 tumours showing significantly more aberrations than stag...
Autores principales: | Partridge, M, Emilion, G, Pateromichelakis, S, A'Hern, R, Lee, G, Phillips, E, Langdon, J |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1999
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362810/ https://www.ncbi.nlm.nih.gov/pubmed/10206299 http://dx.doi.org/10.1038/sj.bjc.6990290 |
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