Radiation-induced G(1) arrest is not defective in fibroblasts from Li-Fraumeni families without TP53 mutations

Radiation-induced G(1) arrest was studied in four classes of early passage skin fibroblasts comprising 12 normals, 12 heterozygous (mut/wt) TP53 mutation-carriers, two homozygous (mut/–) TP53 mutation-carriers and 16 strains from nine Li-Fraumeni syndrome or Li-Fraumeni-like families in which no TP5...

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Detalles Bibliográficos
Autores principales: Boyle, J M, Greaves, M J, Camplejohn, R S, Birch, J M, Roberts, S A, Varley, J M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362814/
https://www.ncbi.nlm.nih.gov/pubmed/10206274
http://dx.doi.org/10.1038/sj.bjc.6690265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362814/
https://www.ncbi.nlm.nih.gov/pubmed/10206274
http://dx.doi.org/10.1038/sj.bjc.6690265

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