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Radiation-induced G(1) arrest is not defective in fibroblasts from Li-Fraumeni families without TP53 mutations
Radiation-induced G(1) arrest was studied in four classes of early passage skin fibroblasts comprising 12 normals, 12 heterozygous (mut/wt) TP53 mutation-carriers, two homozygous (mut/–) TP53 mutation-carriers and 16 strains from nine Li-Fraumeni syndrome or Li-Fraumeni-like families in which no TP5...
Autores principales: | Boyle, J M, Greaves, M J, Camplejohn, R S, Birch, J M, Roberts, S A, Varley, J M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1999
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362814/ https://www.ncbi.nlm.nih.gov/pubmed/10206274 http://dx.doi.org/10.1038/sj.bjc.6690265 |
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