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Microsatellite instability in sporadic colorectal cancer is not an independent prognostic factor

Hereditary non-polyposis colorectal cancer (HNPCC) is linked to an inherited defect in the DNA mismatch repair system. DNA from HNPCC tumours shows microsatellite instability (MSI). It has been reported that HNPCC patients have a better prognosis than patients with sporadic colorectal cancer. We exa...

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Detalles Bibliográficos
Autores principales: Salahshor, S, Kressner, U, Fischer, H, Lindmark, G, Glimelius, B, Påhlman, L, Lindblom, A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362857/
https://www.ncbi.nlm.nih.gov/pubmed/10496341
http://dx.doi.org/10.1038/sj.bjc.6690676