The distinct role of CD4(+) and CD8(+) T-cells during the anti-tumour effects of targeted superantigens

To target T-cells to the tumour area we created a recombinant protein of the bacterial superantigen (SAg) Staphylococcal enterotoxin A (SEA) and the Fab-fragment of a tumour-reactive antibody. This antibody-targeted SAg immunotherapy therapy has been shown to be highly efficient, eliminating > 95...

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Detalles Bibliográficos
Autores principales: Litton, M J, Dohlsten, M, Rosendahl, A, Ohlsson, L, Søgaard, M, Andersson, J, Andersson, U
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362868/
https://www.ncbi.nlm.nih.gov/pubmed/10496366
http://dx.doi.org/10.1038/sj.bjc.6690701

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362868/
https://www.ncbi.nlm.nih.gov/pubmed/10496366
http://dx.doi.org/10.1038/sj.bjc.6690701

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