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The distinct role of CD4(+) and CD8(+) T-cells during the anti-tumour effects of targeted superantigens
To target T-cells to the tumour area we created a recombinant protein of the bacterial superantigen (SAg) Staphylococcal enterotoxin A (SEA) and the Fab-fragment of a tumour-reactive antibody. This antibody-targeted SAg immunotherapy therapy has been shown to be highly efficient, eliminating > 95...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
1999
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362868/ https://www.ncbi.nlm.nih.gov/pubmed/10496366 http://dx.doi.org/10.1038/sj.bjc.6690701 |