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Identification of tumour-associated and germ line p53 mutations in canine mammary cancer

Mutations of the tumour suppressor p53 gene are found in a number of spontaneous canine cancers and may contribute to increased cytogenetic alterations and tumour formation. Using reverse transcription and DNA amplification, we isolated p53 cDNA from normal and tumour tissue of ten canine mammary ca...

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Detalles Bibliográficos
Autores principales: Veldhoen, N, Watterson, J, Brash, M, Milner, J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362910/
https://www.ncbi.nlm.nih.gov/pubmed/10507764
http://dx.doi.org/10.1038/sj.bjc.6690709