Detection of loss of heterozygosity at RAD51, RAD52, RAD54 and BRCA1 and BRCA2 loci in breast cancer: pathological correlations

Loss of heterozygosity (LOH) in loci of the 15q15.1, 12p13, 1p32, 17q21 and 13q12–13 regions may collaborate in the inactivation of RAD51, RAD52, RAD54, BRCA1, BRCA2 and possibly other genes implicated in the repair of double-stranded DNA and in DNA recombination. We investigate allelic losses in mi...

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Detalles Bibliográficos
Autores principales: Gonzalez, R, Silva, J M, Dominguez, G, Garcia, J M, Martinez, G, Vargas, J, Provencio, M, España, P, Bonilla, F
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362917/
https://www.ncbi.nlm.nih.gov/pubmed/10507777
http://dx.doi.org/10.1038/sj.bjc.6690722

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362917/
https://www.ncbi.nlm.nih.gov/pubmed/10507777
http://dx.doi.org/10.1038/sj.bjc.6690722

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