Fish oil supplementation enhanced CPT-11 (irinotecan) efficacy against MCF7 breast carcinoma xenografts and ameliorated intestinal side-effects

The cancer chemotherapeutic efficacy of the topoisomerase I inhibitor, CPT-11 (irinotecan) is often limited by the induction of severe delayed diarrhoea. In animal studies, CPT-11 use is associated with histopathological damage to the mucosa of the small and large intestines. Results from the presen...

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Detalles Bibliográficos
Autores principales: Hardman, W E, Moyer, M P, Cameron, I L
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362926/
https://www.ncbi.nlm.nih.gov/pubmed/10507768
http://dx.doi.org/10.1038/sj.bjc.6690713

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362926/
https://www.ncbi.nlm.nih.gov/pubmed/10507768
http://dx.doi.org/10.1038/sj.bjc.6690713

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