The acridonecarboxamide GF120918 potently reverses P-glycoprotein-mediated resistance in human sarcoma MES-Dx5 cells

The doxorubicin-selected, P-glycoprotein (P-gp)-expressing human sarcoma cell line MES-Dx5 showed the following levels of resistance relative to the non-P-gp-expressing parental MES-SA cells in a 72 h exposure to cytotoxic drugs: etoposide twofold, doxorubicin ninefold, vinblastine tenfold, taxotere...

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Detalles Bibliográficos
Autores principales: Traunecker, H C L, Stevens, M C G, Kerr, D J, Ferry, D R
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362940/
https://www.ncbi.nlm.nih.gov/pubmed/10576649
http://dx.doi.org/10.1038/sj.bjc.6690791

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362940/
https://www.ncbi.nlm.nih.gov/pubmed/10576649
http://dx.doi.org/10.1038/sj.bjc.6690791

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