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Phase I clinical study applying autologous immunological effector cells transfected with the interleukin-2 gene in patients with metastatic renal cancer, colorectal cancer and lymphoma

Natural killer-like T lymphocytes termed cytokine-induced killer (CIK) cells have been shown to eradicate established tumours in a severe combined immune deficient (SCID) mouse/human lymphoma model. Recently, we demonstrated that CIK cells transfected with cytokine genes possess an improved prolifer...

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Detalles Bibliográficos
Autores principales: Schmidt-Wolf, I G H, Finke, S, Trojaneck, B, Denkena, A, Lefterova, P, Schwella, N, Heuft, H-G, Prange, G, Korte, M, Takeya, M, Dorbic, T, Neubauer, A, Wittig, B, Huhn, D
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362953/
https://www.ncbi.nlm.nih.gov/pubmed/10576658
http://dx.doi.org/10.1038/sj.bjc.6690800