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Phase I clinical study applying autologous immunological effector cells transfected with the interleukin-2 gene in patients with metastatic renal cancer, colorectal cancer and lymphoma
Natural killer-like T lymphocytes termed cytokine-induced killer (CIK) cells have been shown to eradicate established tumours in a severe combined immune deficient (SCID) mouse/human lymphoma model. Recently, we demonstrated that CIK cells transfected with cytokine genes possess an improved prolifer...
Autores principales: | Schmidt-Wolf, I G H, Finke, S, Trojaneck, B, Denkena, A, Lefterova, P, Schwella, N, Heuft, H-G, Prange, G, Korte, M, Takeya, M, Dorbic, T, Neubauer, A, Wittig, B, Huhn, D |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1999
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362953/ https://www.ncbi.nlm.nih.gov/pubmed/10576658 http://dx.doi.org/10.1038/sj.bjc.6690800 |
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