Cargando…

In vivo and in vitro evaluation of combretastatin A-4 and its sodium phosphate prodrug

The anti-tumour effects and mechanism of action of combretastatin A-4 and its prodrug, combretastatin A-4 disodium phosphate, were examined in subcutaneous and orthotopically transplanted experimental colon tumour models. Additionally, the ability of these compounds to directly interfere with endoth...

Descripción completa

Detalles Bibliográficos
Autores principales: Grosios, K, Holwell, S E, McGown, A T, Pettit, G R, Bibby, M C
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362967/
https://www.ncbi.nlm.nih.gov/pubmed/10604728
http://dx.doi.org/10.1038/sj.bjc.6692174