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In vivo and in vitro evaluation of combretastatin A-4 and its sodium phosphate prodrug
The anti-tumour effects and mechanism of action of combretastatin A-4 and its prodrug, combretastatin A-4 disodium phosphate, were examined in subcutaneous and orthotopically transplanted experimental colon tumour models. Additionally, the ability of these compounds to directly interfere with endoth...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1999
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362967/ https://www.ncbi.nlm.nih.gov/pubmed/10604728 http://dx.doi.org/10.1038/sj.bjc.6692174 |