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Reduction in membranous expression of β-catenin and increased cytoplasmic E-cadherin expression predict poor survival in gastric cancer

β-catenin, a component of the E-cadherin–catenin cell adhesion complex, also plays a separate intracellular signalling role, interacting with APC protein. Intracellular accumulation of β-catenin is common in colorectal neoplasia. β-catenin abnormalities are associated with poor survival in gastric c...

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Detalles Bibliográficos
Autores principales: Ramesh, S, Nash, J, McCulloch, P G
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362972/
https://www.ncbi.nlm.nih.gov/pubmed/10604738
http://dx.doi.org/10.1038/sj.bjc.6693437