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Down-regulation of TGF-β receptors in human colorectal cancer: implications for cancer development

Many colorectal cancer cells are resistant to the anti-proliferative effects of transforming growth factor-β (TGF-β). TGF-β also acts as paracrine factor from cancer cells on their mesenchymal cells. The aim of this study was to examine the expression of TGF-β and its receptors in human colorectal c...

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Detalles Bibliográficos
Autores principales: Matsushita, M, Matsuzaki, K, Date, M, Watanabe, T, Shibano, K, Nakagawa, T, Yanagitani, S, Amoh, Y, Takemoto, H, Ogata, N, Yamamoto, C, Kubota, Y, Seki, T, Inokuchi, H, Nishizawa, M, Takada, H, Sawamura, T, Okamura, A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2362997/
https://www.ncbi.nlm.nih.gov/pubmed/10389996
http://dx.doi.org/10.1038/sj.bjc.6690339