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Vesnarinone and glucocorticoids cooperatively induce G(1) arrest and have an anti-tumour effect on human non-small cell lung carcinoma cells grown in nude mice

Vesnarinone, an oral cardiotonic, inhibited the growth of several human non-small cell lung carcinoma cell lines, and its anti-proliferative effects in vitro and in vivo were greatly enhanced by combination with glucocorticoids, but not other steroids. Simultaneous treatment with vesnarinone and dex...

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Detalles Bibliográficos
Autores principales: Honma, Y, Yamamoto-Yamaguchi, Y, Kanatani, Y
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363000/
https://www.ncbi.nlm.nih.gov/pubmed/10389984
http://dx.doi.org/10.1038/sj.bjc.6690327