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Cathepsin-D, urokinase plasminogen activator and type-1 plasminogen activator inhibitor in early breast cancer: an immunohistochemical study of prognostic value and relations to tenascin-C and other factors

Cytosolic determinations of cathepsin-D (cath-D), urokinase plasminogen activator (uPA) and its specific inhibitor PAI-1 have shown an association with adverse prognosis in breast cancer. Our aim was to study the distribution of these markers in small axillary node-negative breast carcinomas using i...

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Detalles Bibliográficos
Autores principales: Jahkola, T, Toivonen, T, Smitten, K von, Virtanen, I, Wasenius, V-M, Blomqvist, C
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363020/
https://www.ncbi.nlm.nih.gov/pubmed/10389993
http://dx.doi.org/10.1038/sj.bjc.6690336