Swainsonine protects both murine and human haematopoietic systems from chemotherapeutic toxicity

The haematopoietic system is sensitive to cytotoxic damage and is often the site of dose-limiting toxicity. We previously reported that swainsonine, an inhibitor of protein glycosylation, reduced the bone marrow toxicity resulting from a single dose of anticancer drugs in otherwise healthy mice. How...

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Detalles Bibliográficos
Autores principales: Klein, J-L D, Roberts, J D, George, M D, Kurtzberg, J, Breton, P, Chermann, J-C, Olden, K
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363022/
https://www.ncbi.nlm.nih.gov/pubmed/10389983
http://dx.doi.org/10.1038/sj.bjc.6690326

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363022/
https://www.ncbi.nlm.nih.gov/pubmed/10389983
http://dx.doi.org/10.1038/sj.bjc.6690326

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