Role of p16/MTS1, cyclin D1 and RB in primary oral cancer and oral cancer cell lines

One of the most important components of G1 checkpoint is the retinoblastoma protein (pRB(110)). The activity of pRB is regulated by its phosphorylation, which is mediated by genes such as cyclin D1 and p16/MTS1. All three genes have been shown to be commonly altered in human malignancies. We have sc...

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Detalles Bibliográficos
Autores principales: Sartor, M, Steingrimsdottir, H, Elamin, F, Gäken, J, Warnakulasuriya, S, Partridge, M, Thakker, N, Johnson, N W, Tavassoli, M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363027/
https://www.ncbi.nlm.nih.gov/pubmed/10389982
http://dx.doi.org/10.1038/sj.bjc.6690505

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363027/
https://www.ncbi.nlm.nih.gov/pubmed/10389982
http://dx.doi.org/10.1038/sj.bjc.6690505

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