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Role of p16/MTS1, cyclin D1 and RB in primary oral cancer and oral cancer cell lines
One of the most important components of G1 checkpoint is the retinoblastoma protein (pRB(110)). The activity of pRB is regulated by its phosphorylation, which is mediated by genes such as cyclin D1 and p16/MTS1. All three genes have been shown to be commonly altered in human malignancies. We have sc...
| Autores principales: | , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
1999
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363027/ https://www.ncbi.nlm.nih.gov/pubmed/10389982 http://dx.doi.org/10.1038/sj.bjc.6690505 |