[Arg(6),D-Trp(7,9),N(me)Phe(8)]-substance P (6–11) activates JNK and induces apoptosis in small cell lung cancer cells via an oxidant-dependent mechanism

[Arg(6),D-Trp(7,9),N(me)Phe(8)]-substance P (6–11) (antagonist G) is a novel class of anti-cancer agent that inhibits small-cell lung cancer (SCLC) cell growth in vitro and in vivo and is entering phase II clinical investigation for the treatment of SCLC. Although antagonist G blocks SCLC cell growt...

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Detalles Bibliográficos
Autores principales: MacKinnon, A C, Armstrong, R A, Waters, C M, Cummings, J, Smyth, J F, Haslett, C, Sethi, T
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363053/
https://www.ncbi.nlm.nih.gov/pubmed/10362111
http://dx.doi.org/10.1038/sj.bjc.6690458

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363053/
https://www.ncbi.nlm.nih.gov/pubmed/10362111
http://dx.doi.org/10.1038/sj.bjc.6690458

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