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[Arg(6),D-Trp(7,9),N(me)Phe(8)]-substance P (6–11) activates JNK and induces apoptosis in small cell lung cancer cells via an oxidant-dependent mechanism
[Arg(6),D-Trp(7,9),N(me)Phe(8)]-substance P (6–11) (antagonist G) is a novel class of anti-cancer agent that inhibits small-cell lung cancer (SCLC) cell growth in vitro and in vivo and is entering phase II clinical investigation for the treatment of SCLC. Although antagonist G blocks SCLC cell growt...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
1999
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363053/ https://www.ncbi.nlm.nih.gov/pubmed/10362111 http://dx.doi.org/10.1038/sj.bjc.6690458 |