A human breast cancer model for the study of telomerase inhibitors based on a new biotinylated-primer extension assay

Telomerase is an RNA-dependent polymerase that synthesizes telomeric DNA (TTAGGG)(n) repeats. The overall goal of our work was to establish human cancer models that can be used to design clinical trials with telomerase inhibitors. The objectives of this study were (1) to set up a human breast cancer...

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Detalles Bibliográficos
Autores principales: Raymond, E, Sun, D, Izbicka, E, Mangold, G, Silvas, E, Windle, B, Sharma, S, Soda, H, Laurence, R, Davidson, K, Hoff, D D Von
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363066/
https://www.ncbi.nlm.nih.gov/pubmed/10424733
http://dx.doi.org/10.1038/sj.bjc.6690526

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363066/
https://www.ncbi.nlm.nih.gov/pubmed/10424733
http://dx.doi.org/10.1038/sj.bjc.6690526

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