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DNA methylation and expression of LINE-1 and HERV-K provirus sequences in urothelial and renal cell carcinomas
Since DNA methylation is considered an important mechanism for silencing of retroelements in the mammalian genome, hypomethylation in human tumours may lead to their reactivation. The methylation status of LINE-1 retroposons was determined in 73 samples of urinary bladder cancers, 34 specimens of re...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
1999
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363067/ https://www.ncbi.nlm.nih.gov/pubmed/10424731 http://dx.doi.org/10.1038/sj.bjc.6690524 |