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p27(KIP1) is abnormally expressed in Diffuse Large B-Cell Lymphomas and is associated with an adverse clinical outcome
Cell cycle progression is regulated by the combined action of cyclins, cyclin-dependent kinases (CDKs), and CDK-inhibitors (CDKi), which are negative cell cycle regulators. p27(KIP1) is a CDKi key in cell cycle regulation, whose degradation is required for G1/S transition. In spite of the absence of...
Autores principales: | , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1999
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363083/ https://www.ncbi.nlm.nih.gov/pubmed/10424746 http://dx.doi.org/10.1038/sj.bjc.6690539 |