Cargando…

The laminin-derived peptide YIGSR (Tyr–Ile–Gly–Ser–Arg) inhibits human pre-B leukaemic cell growth and dissemination to organs in SCID mice

The YIGSR (Tyr–Ile–Gly–Ser–Arg) laminin β1 chain sequence has an inhibitory effect on tumour growth and the metastasis of melanoma and fibrosarcoma cells. In the present study, we investigated whether the multimeric YIGSR peptide (Ac-Y16) has an anti-proliferative effect and/or prevents the metastas...

Descripción completa

Detalles Bibliográficos
Autores principales: Yoshida, N, Ishii, E, Nomizu, M, Yamada, Y, Mohri, S, Kinukawa, N, Matsuzaki, A, Oshima, K, Hara, T, Miyazaki, S
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363142/
https://www.ncbi.nlm.nih.gov/pubmed/10471037
http://dx.doi.org/10.1038/sj.bjc.6690618