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Ribozyme inhibition of the protein kinase Cα triggers apoptosis in glioma cells

Although protein kinase C has been shown to be involved in a wide range of biological functions, the precise role of each isoform in a specific cell function remains to be clarified. Here we demonstrate that a ribozyme specific for the human protein kinase Cα (PKCα), a classical PKC isoform, induces...

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Detalles Bibliográficos
Autores principales: Leirdal, M, Sioud, M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363167/
https://www.ncbi.nlm.nih.gov/pubmed/10408397
http://dx.doi.org/10.1038/sj.bjc.6690560