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Ribozyme inhibition of the protein kinase Cα triggers apoptosis in glioma cells
Although protein kinase C has been shown to be involved in a wide range of biological functions, the precise role of each isoform in a specific cell function remains to be clarified. Here we demonstrate that a ribozyme specific for the human protein kinase Cα (PKCα), a classical PKC isoform, induces...
Autores principales: | Leirdal, M, Sioud, M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1999
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363167/ https://www.ncbi.nlm.nih.gov/pubmed/10408397 http://dx.doi.org/10.1038/sj.bjc.6690560 |
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