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Targeted photodestruction of human colon cancer cells using charged Dougherty chlorin(e6)immunoconjugates
The goal of this study was to develop a strategy for the selective destruction of colorectal cancer cells. Towards this end, photoimmunoconjugates were prepared between the anti-colon cancer monoclonal antibody 17.1A and the photosensitizer (PS) chlorin(e6)(c(e6)). Polylysine linkers bearing several...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363172/ https://www.ncbi.nlm.nih.gov/pubmed/10638967 http://dx.doi.org/10.1054/bjoc.1999.0877 |