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Targeted photodestruction of human colon cancer cells using charged Dougherty chlorin(e6)immunoconjugates

The goal of this study was to develop a strategy for the selective destruction of colorectal cancer cells. Towards this end, photoimmunoconjugates were prepared between the anti-colon cancer monoclonal antibody 17.1A and the photosensitizer (PS) chlorin(e6)(c(e6)). Polylysine linkers bearing several...

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Detalles Bibliográficos
Autores principales: Governatore, M Del, Hamblin, MR, Piccinini, EE, Ugolini, G, Hasan, T
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363172/
https://www.ncbi.nlm.nih.gov/pubmed/10638967
http://dx.doi.org/10.1054/bjoc.1999.0877