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Sample size calculation for clinical trials: the impact of clinician beliefs

The UK Medical Research Council (MRC) randomized trial of gastric surgery, ST01, compared conventional (D1) with radical (D2) surgery. Sample size estimation was based upon the consensus opinion of the surgical members of the design team, which suggested that a change in 5-year survival from 20% (D1...

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Detalles Bibliográficos
Autores principales: Fayers, P M, Cuschieri, A, Fielding, J, Craven, J, Uscinska, B, Freedman, L S
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363196/
https://www.ncbi.nlm.nih.gov/pubmed/10638992
http://dx.doi.org/10.1054/bjoc.1999.0902