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Anti-HER2 antibody enhances the growth inhibitory effect of anti-oestrogen on breast cancer cells expressing both oestrogen receptors and HER2

Anti-oestrogen is effective for the treatment of oestrogen receptor (ER)-positive breast carcinomas, butmost of these tumours become resistant to anti-oestrogen. It has been suggested that anti-oestrogen therapy may induce a HER2signalling pathway in breast cancer cells and this may cause resistance...

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Detalles Bibliográficos
Autores principales: Kunisue, H, Kurebayashi, J, Otsuki, T, Tang, C K, Kurosumi, M, Yamamoto, S, Tanaka, K, Doihara, H, Shimizu, N, Sonoo, H
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363211/
https://www.ncbi.nlm.nih.gov/pubmed/10638965
http://dx.doi.org/10.1054/bjoc.1999.0875