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Anti-HER2 antibody enhances the growth inhibitory effect of anti-oestrogen on breast cancer cells expressing both oestrogen receptors and HER2
Anti-oestrogen is effective for the treatment of oestrogen receptor (ER)-positive breast carcinomas, butmost of these tumours become resistant to anti-oestrogen. It has been suggested that anti-oestrogen therapy may induce a HER2signalling pathway in breast cancer cells and this may cause resistance...
Autores principales: | Kunisue, H, Kurebayashi, J, Otsuki, T, Tang, C K, Kurosumi, M, Yamamoto, S, Tanaka, K, Doihara, H, Shimizu, N, Sonoo, H |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2363211/ https://www.ncbi.nlm.nih.gov/pubmed/10638965 http://dx.doi.org/10.1054/bjoc.1999.0875 |
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